
Sassafras oil, which is extracted from the bark and roots of the Sassafras albidum tree, has been used for various medicinal and culinary purposes. However, due to its high safrole content and potential health risks, its usage has come under scrutiny. In the United States, the Food and Drug Administration (FDA) banned sassafras oil as a food and flavouring additive, and it is listed as a Schedule I drug. This classification means it is considered to have no accepted medical use and a high potential for misuse, making it illegal to buy, possess, manufacture, or distribute in the country. Australia also regulates the importation of safrole and sassafras oil, requiring licences and permits for their import. This paragraph introduces the topic by providing an overview of sassafras oil's historical usage, the concerns surrounding its safrole content, and the legal status of sassafras oil in the United States and Australia.
| Characteristics | Values |
|---|---|
| Sassafras Oil in Australia | Sassafras oil is illegal in Australia without a licence and permit issued under the Customs (Prohibited Imports) Regulations 1956. |
| Sassafras Oil | Sassafras oil is extracted from the bark and roots of the tree Sassafras albidum. |
| Composition | Sassafras oil contains 80% safrole, a colorless, oily liquid with a sweet, warm, spicy flavor. |
| Uses | Sassafras oil has been used as a spice, a flavoring agent, a natural diuretic, and a remedy for urinary tract disorders and kidney problems. It has also been used in aromatherapy, cosmetics, and traditional medicine. |
| Health Risks | Sassafras oil has been linked to liver cancer in rats and is considered hepatotoxic and weakly carcinogenic. It is also toxic at higher levels and can cause serious side effects. |
| Legality in Other Countries | The use of sassafras oil as a food and flavoring additive is banned in the United States due to its high content of safrole and its proven carcinogenic effects. It is also controlled in Canada, New Zealand, and the United Kingdom. |
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What You'll Learn

Sassafras oil is illegal in Australia due to its safrole content
Sassafras oil is a natural oil extracted from the bark and roots of the Sassafras albidum tree. It has been traditionally used for its medicinal properties and as a flavouring agent. However, in Australia, sassafras oil is illegal due to its safrole content.
Safrole is a significant component of sassafras oil, typically comprising about 80% of the oil. It is a colourless, oily liquid with a sweet, warm, spicy flavour. While safrole has been commonly used as a flavouring agent, it has been linked to serious health risks. Studies have shown that safrole can induce liver tumours and cause hepatic cancers in rats when administered in their diet. As a result, the US Food and Drug Administration (FDA) banned the use of safrole and sassafras oil as food and flavouring additives in 1958 due to their high safrole content and proven carcinogenic effects. Many other countries, including Australia, have followed suit and prohibited the use of safrole and sassafras oil in flavours and foods.
The importation of safrole and sassafras oil is strictly regulated in Australia. The Office of Drug Control (ODC) requires importers to hold a licence and permit under the Customs (Prohibited Imports) Regulations 1956 to import these substances. The strict regulations and import restrictions on sassafras oil in Australia are primarily due to the presence of safrole and its associated health risks.
In addition to its use as a flavouring agent, safrole has also been linked to the production of methylenedioxyamphetamine (MDA), a hallucinogenic drug. Sassafras oil, derived from the sassafras plant, contains safrole, which can be used to synthesise MDA. MDA is a controlled substance in many countries, including Australia, due to its potential for misuse and adverse health effects.
While pure sassafras oil may still be available online or in some health food stores, its use as a flavouring agent and food additive is prohibited in Australia due to the presence of safrole. The health risks associated with safrole, including its hepatotoxicity and carcinogenic effects, have led to the strict regulations and illegal status of sassafras oil in Australia.
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Safrole is a hepatocarcinogen and is banned in food and flavouring agents
Sassafras oil, derived from the bark and roots of the sassafras tree, was once widely used for its medicinal properties and as a flavouring agent. However, the discovery of its hepatotoxic effects, specifically the carcinogenic compound safrole, has led to its restriction in food and flavouring agents.
Safrole, a colourless oily liquid with a sweet, warm, spicy flavour, constitutes about 80% of sassafras oil. It is also present in smaller amounts in various spices, including star anise, camphor oil, mace, nutmeg, Japanese wild ginger, California bay laurel, and cinnamon leaf oil.
In the 1960s, studies revealed that the administration of safrole to male and female rats over a period of 150 days to 2 years resulted in hepatic cancers. These findings prompted the United States Food and Drug Administration (FDA) to ban the use of safrole in 1958, specifically prohibiting sassafras bark used in sassafras tea. Many other countries, including Australia, followed suit and banned the use of safrole in flavours and food products.
The FDA classified sassafras and its derivatives, including safrole, as adulterated products and prohibited their sale in the United States. This decision was based on the proven carcinogenic effects of safrole, which induce liver tumours in rats. As a result, sassafras oil is no longer allowed as a food additive or flavouring agent in regulated products. However, pure sassafras oil may still be available online or in some health food stores, and it continues to be used in traditional medicines and remedies.
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Sassafras oil is a hallucinogen and stimulant
Sassafras oil, also known as safrole, is a colourless, oily liquid with a sweet, warm, spicy flavour. It is extracted from the bark and roots of the Sassafras albidum tree. Sassafras oil is a hallucinogen and stimulant with a variety of medicinal properties. It has been used as a spring tonic, antispasmodic, blood purifier, and sweat producer. It is also said to be a cure for rheumatism, skin disease, syphilis, typhus, and dropsy.
The oil has a high safrole content, which has been linked to liver cancer in rats. As a result, the US Food and Drug Administration (FDA) banned the use of sassafras oil as a food and flavouring additive. Several other countries followed suit, prohibiting the use of safrole in flavours. In Australia, the importation of safrole and sassafras oil is prohibited unless the importer holds a valid licence and permit.
Despite the health risks and regulatory restrictions, pure sassafras oil remains accessible online and in select health food stores. It is also used illicitly as a recreational drug, known as methylenedioxyamphetamine (MDA) or simply "sass" or "sally" on the streets. MDA is a controlled substance in many countries, including Australia, and it is illegal to buy, possess, manufacture, or distribute it.
As a stimulant hallucinogen, sassafras produces a heavier high with more energy and visual effects compared to similar drugs like molly. The effects of sassafras tend to be longer-lasting, and it is typically consumed orally in pill, capsule, or powder form. However, it is important to note that the drug comes with inherent risks, and its use can lead to serious side effects or even overdose, especially when combined with other substances.
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It has been used as a traditional medicine and tonic
Sassafras oil has been used as a traditional medicine and tonic. The oil is extracted from the root of the sassafras tree, native to North America, and has been used to treat various ailments and conditions.
Sassafras was traditionally used as a spring tonic or blood purifier and was believed to be effective in treating influenza, arthritis, urinary tract infections, and digestive issues. It was also used to address urinary tract disorders, swelling in the nose and throat, syphilis, bronchitis, high blood pressure in older people, gout, skin problems, and even cancer. In beverages and candy, sassafras was used to flavour root beer, and it was also consumed as a tea.
However, despite its rich history in traditional medicine, sassafras oil is unsafe for human consumption and has been banned for this purpose. This is due to the presence of safrole, a toxic compound found in sassafras oil, which has been linked to liver cancer in animal studies. Consuming just 5 mL of sassafras oil can be fatal for adults, and even lower doses can be deadly for children and infants. In addition to its carcinogenic effects, sassafras oil can also cause sweating, hot flashes, vomiting, high blood pressure, hallucinations, and skin rashes.
While some proponents of complementary and alternative medicine continue to advocate for the use of sassafras, citing its anti-inflammatory and pain-relieving properties, the potential risks associated with its consumption are well-documented. It is important to note that natural products are not always safe, and the lack of scientific information on appropriate dosing further underscores the dangers of using sassafras as a medicine or tonic.
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Sassafras oil is still available online and in health food stores
Sassafras oil, derived from the bark and roots of the Sassafras albidum tree, has been prized for its medicinal properties and distinctive flavour. However, its usage has come under scrutiny due to its safrole content, which comprises about 80% of the oil. Studies in the 1960s linked safrole to liver cancer in rats, prompting regulatory action to prohibit its use in food and flavouring agents.
In Australia, the Office of Drug Control (ODC) includes safrole and sassafras oil on its list of controlled substances. The importation of these substances is prohibited unless the importer holds a valid licence and permit issued under the Customs (Prohibited Imports) Regulations 1956. The ODC provides guidance on obtaining the necessary licences and permits for those seeking to import sassafras oil.
Despite the regulatory restrictions, pure sassafras oil remains accessible through online channels and select health food stores. Its availability in these contexts may be attributed to the ongoing demand for its medicinal and therapeutic properties.
Sassafras oil has a long history of use in folk medicine and as a flavouring agent. Traditionally, it has been employed as a spring tonic, stimulant, antispasmodic, blood purifier, and sweat producer. It has also been used to treat a range of ailments, including rheumatism, skin diseases, syphilis, typhus, and dropsy. Additionally, sassafras oil has been valued for its distinctive flavour, particularly in root beer and various culinary creations.
While sassafras oil may still be obtainable online and in health food stores, it is important to exercise caution. The potential health risks associated with sassafras oil, particularly its hepatotoxic and carcinogenic effects, have been well-documented. Therefore, individuals should carefully consider these risks and consult professional advice before using sassafras oil, especially if they have specific health concerns or are taking other medications.
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Frequently asked questions
Sassafras oil is extracted from the bark and roots of the tree Sassafras albidum. It is also known as Safrole and has been used as a flavouring agent and in traditional medicine.
Sassafras oil is illegal in many countries due to its high safrole content. Safrole has been proven to have carcinogenic effects and cause liver tumours in rats.
Yes, the importation of Sassafras oil is prohibited in Australia unless the importer holds a valid licence and permit.
Sassafras oil is considered toxic and can cause serious side effects, especially if consumed in high doses or combined with other substances. It is also a hallucinogen and can lead to overdose or other adverse reactions.
While Sassafras oil is illegal for internal consumption, it is sometimes used topically as a pediculicide and to relieve stings and bites. It has also been used externally for dental procedures and in the preparation of certain foods and beverages.



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