
The SARS-CoV-2 Omicron variant was first detected in Australia in November 2021, with two cases reported in Sydney. Both individuals had recently returned from southern Africa and entered isolation upon arrival. The Omicron variant quickly spread across the globe, with cases reported in numerous countries. In Australia, the Omicron wave of 2021-2022 resulted in a significant health burden, particularly in New South Wales, where it was the dominant variant. Research suggests that COVID-19 vaccinations played a crucial role in preventing thousands of deaths among older Australians during this period.
| Characteristics | Values |
|---|---|
| First cases in Australia | Two travellers who arrived in Sydney from Africa |
| Date | 29 November 2021 |
| Vaccination status of first cases | Fully vaccinated |
| Number of cases in New South Wales, Australia | 64 |
| Deaths prevented by COVID-19 vaccination campaign | 18,000 among older Australians in NSW during the early Omicron era |
| Vaccines used in Australia | Comirnaty (Pfizer), Spikevax (Moderna), Vaxzevria (AstraZeneca), and Nuvaxovid (Novavax) |
| Length of stay in hospital | Increased with age group |
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What You'll Learn
- Omicron was detected in Sydney, Australia, in two travellers from Africa
- Australia's COVID-19 vaccine campaign prevented thousands of deaths before the Omicron spread
- Australia's Department of Health has not yet decided to scrap its recommendation that people with COVID-19 stay home for five days
- Omicron BA.1 and BA.4-5 vaccines are available as a booster dose in Australia
- A study found that the length of hospital stays in New South Wales, Australia, increased with age during the Omicron wave

Omicron was detected in Sydney, Australia, in two travellers from Africa
The Omicron variant was first detected in Sydney, Australia, in two travellers from Africa. The two people, who were fully vaccinated, entered isolation upon arrival in Sydney. 12 other travellers from southern Africa also entered quarantine for 14 days, while about 260 other passengers and crew on the flight were directed to isolate.
The detection of the Omicron variant in Australia prompted concerns about its potential impact on the country's COVID-19 situation. To address this, Australia's Department of Health emphasised the importance of vaccinations, stating that COVID-19 vaccinations may have prevented almost 18,000 deaths among older Australians in New South Wales during the early Omicron wave. The Department also noted that the protective benefits of the vaccines far outweigh the rare risk of side effects.
Furthermore, a computer simulation conducted by researchers from universities in Melbourne and Tel Aviv found that the death rate in Australia during the Omicron wave would have been approximately six times higher in the absence of a vaccination campaign. The simulation attributed the success of the vaccination campaign to high levels of engagement by Australians and the achievement of high vaccination rates.
As of March 2023, four main COVID-19 vaccines have been in use in Australia: Comirnaty (Pfizer), Spikevax (Moderna), Vaxzevria (AstraZeneca), and Nuvaxovid (Novavax). Bivalent vaccines for both mRNA vaccines have also been registered in the country, covering the Omicron BA.1 and BA.4-5 variants. The Therapeutic Goods Administration (TGA) closely monitors reports of suspected side effects and encourages individuals to report any suspected side effects.
In addition to the vaccination efforts, Australia has also conducted studies to understand the impact of the Omicron variant on hospital length of stay. One such study, focusing on New South Wales, found that the length of stay in the ward increased with age, although this trend was not as prominent in ICU pathways.
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Australia's COVID-19 vaccine campaign prevented thousands of deaths before the Omicron spread
Australia's COVID-19 vaccine campaign has been deemed a success in reducing mortality rates during the 2022 Omicron outbreak. A research team from universities in Melbourne and Tel Aviv used computer simulations to predict what the death toll would have been without a vaccine campaign. The results indicated that the vaccination drive prevented 17,760 deaths among NSW residents aged 50 and above, which is approximately six times the actual death toll. The success of the campaign has been attributed to the Australian public's high engagement with the vaccination drive, achieving high vaccination rates just before the 2022 Omicron outbreak.
The Australian government implemented a national vaccination campaign against COVID-19 beginning on February 22, 2021. While the rollout was criticised for being delayed compared to other high-income countries, Australia achieved one of the highest vaccination rates globally by the end of 2021, with over 85% of its eligible population fully vaccinated with two doses. This rapid increase in vaccination rates ensured high levels of protection for the population when the Omicron variant arrived.
The computer simulation study also assessed the impact of booster shots. It was found that the booster campaign prevented 1,860 deaths among the 50+ population in NSW. Furthermore, the study estimated that if NSW had fully vaccinated its 50+ population earlier, by July 28, 2021, an additional 440 deaths could have been averted. The overall impact of the vaccination campaign in NSW is estimated to have prevented tens of thousands of deaths, demonstrating its critical role in mitigating the impact of the Omicron outbreak.
The success of Australia's COVID-19 vaccine campaign is evident in the country's increase in life expectancy from 2019 to 2021, despite the challenges posed by the Omicron variant. This achievement highlights the relative success of Australia's handling of the pandemic, particularly in comparison to other nations. The high vaccination rates and public engagement with the campaign played a pivotal role in preventing a more severe outcome during the Omicron wave.
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Australia's Department of Health has not yet decided to scrap its recommendation that people with COVID-19 stay home for five days
The Omicron variant of the coronavirus was first detected in Australia in November 2021. Two travellers who arrived in Sydney from southern Africa via Doha, Qatar, were the country's first cases. Both individuals were fully vaccinated and entered isolation upon arrival.
In April 2024, the US Center for Disease Control (CDC) proposed to scrap its five-day COVID-19 isolation recommendations. Australia's Department of Health has not yet decided to follow suit. The Australian government continues to recommend that people who test positive for COVID-19 stay at home and avoid contact with people who are at higher risk of severe disease.
The Department's guidelines also recommend avoiding "high-risk settings," such as hospitals and care facilities, for at least seven days or until symptoms have subsided. Additionally, individuals should wear masks and work from home whenever possible. These recommendations are in place to protect the most vulnerable members of society and to reduce the spread of the virus.
While Australia has lifted some COVID-19 restrictions, such as mandatory face masks on flights and in certain public settings, the decision to scrap the five-day isolation period is yet to be made. The country's Chief Medical Officer, Paul Kelly, acknowledged the low rates of COVID-19 transmission but warned that the pandemic is not finished.
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Omicron BA.1 and BA.4-5 vaccines are available as a booster dose in Australia
Omicron was first detected in Australia in November 2021, when two travellers who arrived in Sydney from southern Africa tested positive for the variant. Since then, Australia has been taking proactive measures to combat the spread of Omicron and protect its citizens.
In July 2022, Moderna received provisional registration in Australia from the Therapeutic Goods Administration (TGA) for its COVID-19 vaccine, Spikevax, for children aged six months to five years. This was a significant development, as children under six were previously not eligible for COVID-19 vaccination in the country.
Moreover, Moderna's Omicron-based bivalent booster vaccine, mRNA-1273.222, has also been granted provisional approval in Australia. This vaccine targets the BA.4 and BA.5 subvariants of the Omicron variant and is approved for individuals aged 18 years and older. The TGA's decision was based on the vaccine's ability to provide active immunisation and prevent COVID-19 infections caused by these subvariants.
In addition to Moderna's vaccine, Pfizer and BioNTech have also received a positive nod from Australia's TGA for their bivalent COVID-19 vaccine, Comirnaty. This vaccine is designed to provide active immunisation against the original COVID-19 strain and the Omicron BA.4 and BA.5 subvariants. The provisional determination allows Pfizer to apply for the vaccine's provisional registration for individuals aged 12 and older.
These developments in vaccine technology demonstrate Australia's ongoing commitment to protecting its citizens from the evolving threats posed by COVID-19 and its variants. By offering booster doses that specifically target Omicron subvariants, Australia is taking a proactive approach to public health and ensuring its residents have access to the latest defences against the virus.
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A study found that the length of hospital stays in New South Wales, Australia, increased with age during the Omicron wave
The Omicron variant was first identified in Australia in November 2021, with two cases detected in Sydney. Both individuals had recently travelled from southern Africa and entered isolation upon arrival. The Omicron variant began to spread rapidly across the country, with a total of 826,942 case notifications reported over a two-month period from December 2021 to January 2022. This surge in cases resulted in a peak hospital occupancy of 2,943 on 25 January 2022.
During this period, a study was conducted to estimate the length of stay distributions of hospitalised COVID-19 cases in New South Wales, Australia, during a mixed Omicron-Delta epidemic. The study analysed data from 19,574 individuals who underwent a competing-risk survival analysis of COVID-19 clinical progression. The results showed that the mean length of stay for individuals discharged directly from the ward without an ICU stay varied by age group. For those aged 0-39, the mean length of stay was 2.16 days, while it increased to 3.93 days for the 40-69 age group and 7.61 days for individuals aged 70 and above.
The study also considered data from the Hunter New England Local Health District, where Omicron was the only circulating variant. In this region, the mean ward-to-discharge length of stays were 2.05 days for the 0-39 age group, 2.92 days for the 40-69 age group, and 6.02 days for individuals aged 70 and above. These findings indicate that hospital length of stay was substantially reduced during the mixed Omicron-Delta epidemic compared to the prior Delta epidemic, despite the increased infection burden.
Additionally, the study analysed the risks of severe outcomes, such as ICU admission and mortality, which were found to increase with age. Care home residents aged 65 and above were associated with an increased risk of hospital mortality and a decreased risk of ICU admission. The length of stay was also influenced by factors such as vaccination status and clinical knowledge, treatment, and patient management improvements.
Furthermore, a separate computer simulation study predicted that Australia's COVID-19 vaccine campaign prevented thousands of deaths among older Australians in New South Wales during the early Omicron era. The research team attributed this success to high levels of public engagement and the achievement of high vaccination rates before the Omicron wave hit the country.
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Frequently asked questions
Yes, the Omicron variant was first detected in Australia in November 2021 when two travellers from southern Africa tested positive after landing in Sydney.
The Omicron variant caused a wave of COVID-19 infections in Australia in 2021 and 2022. Studies suggest that COVID-19 vaccinations prevented almost 18,000 deaths among older Australians in New South Wales during the early Omicron wave.
The four main COVID-19 vaccines available in Australia during the Omicron wave were Comirnaty (Pfizer), Spikevax (Moderna), Vaxzevria (AstraZeneca), and Nuvaxovid (Novavax).
During the mixed Omicron-Delta epidemic in New South Wales, Australia, it was found that the mean length of stay for individuals who were discharged directly from the ward without an ICU admission decreased. However, the length of stay in the ward increased with age group.










































