
Codeine is an opioid medicine used to relieve mild pain and suppress a dry cough. It is now a prescription-only medicine in Australia, with all medicines containing codeine requiring a prescription since 1 February 2018. This change was implemented to address the harm associated with the excessive use and misuse of codeine-containing analgesics, which contributed to severe adverse health outcomes, including liver damage, gastrointestinal perforations, respiratory depression, and death. While codeine can be an effective treatment for short-term pain relief, it is important to obtain it safely through a prescription from a doctor to avoid potential health risks.
| Characteristics | Values |
|---|---|
| Date of change in regulation | 1 February 2018 |
| Previous availability | Over-the-counter |
| Current availability | Prescription-only |
| Average per-capita consumption change | Decreased by 37% nationally |
| Consumption change in regional areas | Decreased by 51% |
| Consumption change in cities | Decreased by 38% |
| Consumption change in South Australia | Decreased in Adelaide city sites |
| Previous pack size | Up to 100 tablets |
| Current pack size | Maximum of 50 tablets |
| Alternative medicines | Paracetamol/ibuprofen combinations |
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What You'll Learn

Codeine is prescription-only in Australia
Codeine is a commonly used opioid medicine for pain relief and to suppress a dry cough. It is now a prescription-only medicine in Australia, with tighter restrictions being placed on its availability since 2010.
In 2010, codeine-containing analgesics were up-scheduled from 'Pharmacy Only Medicines' to 'Pharmacist Only Medicines', requiring a pharmacist to be involved in the sale. This was due to increasing concern regarding inappropriate use. In addition, the pack sizes for low-dose codeine were restricted from up to 100 tablets to a maximum of 50. However, concerns surrounding harm associated with over-the-counter codeine persisted.
In 2013, 33% of people who had misused pharmaceuticals reported using over-the-counter codeine, which increased to 75% in 2016. Calls to Australian poison centres regarding codeine misuse also increased from 2004 to 2015, and the proportion of people seeking opioid substitution therapy for codeine dependence continued to climb, increasing from 2.7% in 2014 to 4.6% in 2016. As a result, in December 2016, the Australian Therapeutic Goods Administration (TGA) announced that codeine-containing analgesics would become prescription-only medicines from February 2018.
From 1 February 2018, all medicines containing codeine required a prescription in Australia. This change was implemented to restrict access to codeine and reduce the potential harm caused by its misuse. The rescheduling of codeine led to a decrease in its consumption, with average per-capita consumption decreasing by 37% nationally immediately after the change.
Codeine is now only available with a prescription from a doctor in Australia. If you are taking codeine, it is important to not stop taking it suddenly, as you may experience withdrawal symptoms.
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Managing without over-the-counter codeine
Since 1 February 2018, codeine has been a prescription-only medicine in Australia. This change was implemented due to the substantial evidence of harm from the abuse or misuse of codeine-containing medicines, including liver damage, gastrointestinal perforations, respiratory depression, and death. Codeine-related deaths in Australia more than doubled from 2000 to 2009, highlighting the seriousness of this issue.
If you were previously using over-the-counter codeine for pain relief, there are alternative options available. Paracetamol/ibuprofen combinations in a single pill can be an effective alternative for short-term pain management. This combination has been shown to provide similar pain relief to low-dose codeine products without the same risks of abuse and adverse health outcomes.
It is important to remember that opioids, including codeine, are typically recommended only when other forms of non-opioid pain relief have been unsuccessful. Even with a prescription, codeine may not be the first option for pain relief. Other opioid medicines are often preferred as they are more effective for most people.
If you are experiencing chronic pain, it is best to consult with a healthcare professional to determine the most suitable treatment option. Services such as healthdirect Australia offer free advice from nurses and doctors who can provide guidance on pain management. They can also help address any concerns related to codeine dependence or withdrawal, which should be carefully managed under medical supervision.
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Codeine alternatives
Since 1 February 2018, codeine has been a prescription-only medicine in Australia. This change was implemented by the Department of Health through the Therapeutic Goods Administration (TGA) to ensure that regulation protects public health and safety.
Codeine is an opioid medicine used to relieve mild pain and suppress a dry cough. It is not usually recommended for the treatment of chronic (long-term) pain. Codeine doesn't work for everyone, as some people's bodies are unable to process it due to an inherited genetic difference.
If you are experiencing pain, there are alternative treatments available. Paracetamol/ibuprofen combinations may be used as an alternative to codeine-based analgesics for the short-term management of pain. These combinations are available as a single pill and can be purchased over the counter.
If you are unsure about which treatment option is best for you, it is recommended that you speak to a doctor or pharmacist.
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History of codeine misuse in Australia
Codeine is an opioid drug that acts on opioid receptors in the brain. It is often used as a pain killer, or in cold and flu medication, and cough mixtures. Globally, it is the most commonly used opioid. In Australia, prior to legislative changes in 2018, codeine was the most commonly used opioid analgesic, with consumption exceeding that of the United States, despite Australia's much smaller population.
In December 2016, the Australian government announced that low-strength codeine would be rescheduled and no longer available for purchase over the counter. This came into effect in February 2018. The aim of this change was to reduce misuse and abuse of codeine, and to give pharmacists a greater role in pain management. This change was in response to a concerning increase in paracetamol poisonings and resulting liver damage in Australia over the previous decade. There had also been a 50% increase in overall poisoning deaths in the country over the same period.
Prior to the legislative changes, there had been a significant upward trend in calls relating to codeine misuse. A retrospective analysis of calls made to an Australian Poisons Information Centre between 2004 and 2015 found an average annual increase of 20% over the 12-year period for calls relating to misuse of paracetamol-codeine containing products, and 18% for calls relating to misuse of ibuprofen-codeine containing products. Another study, which assessed coronial reports Australia-wide for the period 2000-2013 where codeine toxicity or overdose was recorded, found a similar increase in codeine-related deaths.
Following the legislative changes, there was a 50% reduction in the monthly rate of codeine-related poisoning calls, and codeine sales halved. There was also a 53% reduction in the number of codeine-related hospital presentations.
Despite these positive outcomes, there was a potential disadvantage to the codeine rescheduling identified by pharmacists in a study by Mishriky, Stupans et al. (2019). This included the increased burden on general practitioners and patients who now needed to see a doctor for pain management, and the potential for people to switch to using stronger opioid analgesics. However, subsequent studies found that this latter concern did not eventuate, with no increase seen in the use of stronger opioids.
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Codeine consumption in regional Australia
Codeine is an opioid medicine used to relieve mild pain and suppress a dry cough. It is now a prescription-only medicine in Australia, with all medicines containing codeine requiring a prescription since 1 February 2018. This change was implemented to address the harm associated with the excessive use and misuse of codeine-containing analgesics, which can lead to life-threatening adverse effects, including liver damage, gastrointestinal perforations, respiratory depression, and death.
Prior to this rescheduling, codeine was available as an over-the-counter medicine in Australia, which contributed to its widespread consumption. A wastewater-based evaluation conducted between August 2016 and August 2019 revealed that per-capita consumption of codeine decreased by 37% nationally immediately after the rescheduling. This decrease was sustained until August 2019, with locations that had the least pharmacy access experiencing a greater reduction in codeine consumption.
Interestingly, the decrease in codeine consumption varied between regional areas and major cities. Regional sites experienced a smaller decrease in codeine consumption compared to cities, with a 32% reduction compared to 38% in urban areas. This finding aligns with a codeine utilization study that reported the highest utilization rates of codeine in the most remote areas. The limited healthcare services and treatment options in regional and remote areas outside major urban centers may contribute to this trend, as patients may self-manage pain with products like codeine.
The transition to prescription-only codeine prompted the development of clinical advice to manage patients requesting codeine or those who may be codeine-dependent. Alternative over-the-counter products, such as paracetamol/ibuprofen combinations, were recommended for pain management. However, Australian dentists appear to have contributed to the misuse of pharmaceutical opioids, with a significant increase in opioid prescriptions observed after the codeine restriction. This highlights the importance of educational efforts targeting the appropriate use of opioids and patient selection.
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Frequently asked questions
Codeine is a prescription-only medicine in Australia since 1 February 2018. You can no longer buy it over the counter at pharmacies. You will need a prescription from your doctor to obtain codeine.
The decision to make codeine prescription-only was made to reduce the harm associated with its misuse. There was a significant increase in codeine-related deaths from 2000 to 2009, and concerns about its overuse.
Paracetamol and ibuprofen combinations are recommended as an alternative to codeine for short-term pain management.
Codeine is an opioid medicine used to relieve mild to moderate pain and suppress a dry cough.
It is advised to consult with your doctor before stopping codeine, as you may experience withdrawal symptoms.























