Mesothelioma In Australia: A Devastating Toll

how many people in australia have mesothelioma

Australia has one of the highest rates of mesothelioma in the world, with around 700–800 new cases diagnosed each year. Mesothelioma is a rare cancer that develops primarily in the lining of the lungs, chest, abdomen, heart, and reproductive organs. It is caused by exposure to asbestos dust and fibres, and Australia was one of the world's highest consumers of asbestos per capita. In 2020, there were 701 deaths from mesothelioma in Australia, and in 2021, 708 deaths were recorded. On average, two people are diagnosed with mesothelioma in Australia each day, and the median age at diagnosis is 75–77 years old.

Characteristics Values
Number of new cases diagnosed in 2018 811
Number of new cases diagnosed in 2021 637
Number of new cases diagnosed in 2022 904
Number of deaths in 2020 696
Number of deaths in 2021 708
Number of deaths in 2022 (estimated) 761
Median age at diagnosis in 2020 75
Median age at diagnosis in 2021 77
Median age at diagnosis in 2022 75
Percentage of male patients 60-80%
1-year relative survival rate since 1988-1992 Increased
5-year relative survival rate since 1989-1993 Increased
Risk of being diagnosed with mesothelioma by the age of 85 (2022) 1 in 319 (0.31%)
Risk of dying from mesothelioma by the age of 85 (2022) 1 in 396 (0.25%)
Cause of mesothelioma Exposure to asbestos
States with the highest number of cases New South Wales

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Mesothelioma cases in Australia: 700-800 new cases annually

Australia has one of the highest rates of mesothelioma in the world, with 700 to 800 new cases diagnosed annually. Mesothelioma is a rare cancer that develops in the lining of the lungs, chest, abdomen, heart, and reproductive organs. It is caused by exposure to asbestos dust and fibres, and there is no safe level of exposure. The use of asbestos was common in Australia in the past, and it was one of the world's highest consumers of asbestos per capita. As a result, the country continues to see high rates of mesothelioma diagnoses.

In 2021, 637 cases of mesothelioma were diagnosed and reported to the Australian Mesothelioma Registry (AMR), with a median age at diagnosis of 77. This is a slight decrease from the 722 cases diagnosed in 2020, which had a median age at diagnosis of 75. The AMR collects exposure information and distributes annual reports about its findings. The Cancer Institute of New South Wales manages the register.

The number of mesothelioma cases in Australia has been steadily increasing over the past four decades. In 2018, there were 811 new cases diagnosed, and it is estimated that there will be over 900 new cases in 2022. Men are more likely to be diagnosed with mesothelioma than women, and the demographics of Australian mesothelioma patients align with global trends, with approximately 80% of patients being male and the average age being 75 years old.

The high incidence of mesothelioma in Australia is attributed to the past prevalence of asbestos in the country. Asbestos mining occurred locally until about 1983, and over 1.5 million tonnes of asbestos were imported between the 1930s and mid-1980s. Asbestos was widely used in the construction industry and various other industries during this time. While the use of asbestos has been prohibited in Australia since 2003, the legacy of its past use continues to impact the health of Australians, and it is expected that high rates of mesothelioma diagnoses will persist in the coming years.

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Mesothelioma survival rates: 6.8% chance of surviving 5 years post-diagnosis

Mesothelioma is an often-fatal disease that affects the lining of the lungs, heart, abdominal cavity, or testicles. It is caused primarily by exposure to asbestos, and Australia has a history of asbestos mining and use. In 2014–2018, individuals diagnosed with mesothelioma had a 6.8% chance of surviving for five years post-diagnosis compared to their counterparts in the general Australian population. This figure represents a slight improvement from the 5-year survival rate of 5.6% between 1989 and 1993.

It is important to note that survival rates for mesothelioma can vary depending on several factors, including age, gender, overall health, and the type and stage of cancer at diagnosis. For instance, younger patients tend to have higher 5-year survival rates than older patients, likely due to their generally better health. Additionally, female patients generally have better survival rates than male patients.

The type of mesothelioma also plays a significant role in survival rates. Pleural mesothelioma, which occurs in the lining of the lungs, is the most common and aggressive type, with a poorer prognosis. Peritoneal mesothelioma, which affects the lining of the abdominal cavity, is the second most common type and is associated with more positive prognoses and better treatment options. Rarer forms, such as pericardial mesothelioma (affecting the heart) and testicular mesothelioma, have lower survival rates due to limited treatment options.

While mesothelioma has historically been a fatal diagnosis for most, scientific advances are improving survival rates. These include earlier detection methods, new treatments, and innovative therapies such as immunotherapy and mesothelioma vaccines. Clinical trials are also underway to find better treatments and drugs to combat the disease. As a result, more patients are living longer after diagnosis, with some achieving five-year and even ten-year survival.

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Mesothelioma in New South Wales: the state with the highest number of deaths

Mesothelioma is an often fatal cancer caused by exposure to asbestos. In Australia, the disease is responsible for the deaths of more than 700 people each year. The highest number of mesothelioma deaths in Australia have occurred in New South Wales, the first state in the country to mine asbestos.

New South Wales produced the largest amount of chrysotile and amphibole asbestos. The incidence of the disease in this state nearly doubled in the 20 years between 1987 and 2006. The rate among females in New South Wales tripled during that time. Many cases were attributed to secondhand asbestos exposure.

The Wittenoom mine in Western Australia was a significant source of asbestos. Of the 7,000 individuals who worked at the Wittenoom mine from the 1930s to 1966, an estimated 10% have died or will die of mesothelioma. The Western Australian government has warned that unauthorised visits to Wittenoom can lead to prosecution.

Another source of asbestos exposure in New South Wales was the Woodsreef mine, located near the township of Barraba. Abandoned by its operators in the 1980s, the mine left behind approximately 25 million tons of asbestos waste. Asbestos fibres were visible, and the site continues to pose a risk of asbestos exposure more than 25 years after mining operations ceased.

The Bernie Banton Centre at Concord Hospital in Sydney, New South Wales, is the world's first stand-alone research facility dedicated to the treatment and prevention of asbestos-related diseases. It houses the Asbestos Disease Research Institute.

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Mesothelioma causes: asbestos exposure, asbestos mining, and asbestos products

Mesothelioma is a rare cancer of the thin membranes that line the chest and abdomen. In Australia, around 700 people die from the disease each year. The state with the highest number of deaths is New South Wales, which was the first state in the country to mine asbestos.

Asbestos exposure is directly connected to mesothelioma. When asbestos fibres are inhaled or ingested, they can become lodged in the lining of the chest or abdomen, leading to inflammation and scarring that can cause serious health problems. Asbestos fibres can be released into the air when products containing asbestos are disturbed. These fibres can remain in the lungs for a long time, causing damage over many years. All forms of asbestos are considered hazardous, but amphibole forms may be more harmful than chrysotile as they tend to stay in the lungs longer.

Occupational exposure to asbestos is a significant risk factor for mesothelioma. Miners and industrial workers, such as those in shipyards, boiler rooms, and power plants, are among the highest-risk groups. In Australia, asbestos was mined at the Woodsreef mine in New South Wales, which was abandoned in the 1980s with approximately 25 million tons of asbestos waste left behind. The legacy of this and other mining sites means that Australian workers in certain trades are at a higher risk of mesothelioma than the general population.

In addition to occupational exposure, individuals can be exposed to asbestos in older homes, public buildings, and the environment. Asbestos was commonly used in building materials, vehicle parts, and military equipment, so construction workers, auto mechanics, and veterans are also at an increased risk of mesothelioma. Family members of asbestos workers are at risk of secondary exposure from fibres brought into the home on clothing, skin, and hair.

While smoking does not appear to increase the risk of mesothelioma directly, studies have shown that the combination of smoking and asbestos exposure significantly increases the risk of lung cancer.

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Mesothelioma treatment: immunotherapy, chemotherapy, and clinical trials

Mesothelioma is a rare and fatal cancer with limited treatment options. In Australia, it is estimated that a person has a 1 in 319 (or 0.31%) risk of being diagnosed with mesothelioma by the age of 85. In 2022, it is estimated that 904 new cases of mesothelioma will be diagnosed in Australia (714 males and 190 females). In 2021, 637 cases were diagnosed and reported to the Australian Mesothelioma Registry (AMR), with a median age at diagnosis of 77.

Immunotherapy and chemotherapy are the two main treatment options for mesothelioma. Immunotherapy improves the immune system's ability to find and attack mesothelioma cancer. Mesothelioma cells can often go undetected by the body's natural immune system. Immunotherapy helps overcome this by training immune cells to recognize the cancer. Doctors often use immunotherapy alongside other mesothelioma treatments, such as chemotherapy or surgery, to improve outcomes. Combining immunotherapy with chemotherapy has been shown to improve response rates and survival for many patients. For example, patients with unresectable pleural mesothelioma now have FDA-approved immunotherapy options as part of their frontline treatment plan, which has resulted in extended survival compared to previous therapies. Clinical trials have shown that immunotherapy can extend survival. For instance, patients who received immunotherapy in addition to chemotherapy lived over a year longer than those who received only chemotherapy.

There are several immunotherapy treatments for mesothelioma currently in clinical trials. These include CAR T-cell therapy, cancer vaccines, and oncolytic viruses. Clinical trials allow patients to access innovative therapies early and can provide new hope for improved quality of life and extended survival. For instance, the DREAM3R and CheckMate 743 trials compare immunotherapy to chemotherapy to identify the most effective treatment. The PrE0505 clinical trial, sponsored by PrECOG, LLC, a not-for-profit company that supports the scientific mission of the ECOG-ACRIN Cancer Research Group, showed that concurrent durvalumab with platinum-based chemotherapy has promising clinical activity. The survival for patients with epithelioid MPM (malignant pleural mesothelioma) exceeded two years, and some patients with epithelioid MPM who enrolled in the clinical trial continue to be free from tumor progression.

In addition to these treatments, scientists are developing targeted therapies that attack specific genes or proteins that help mesothelioma grow or spread. These advances hold promise for improving life expectancy in hard-to-treat cases.

Frequently asked questions

On average, 700 to 800 people are diagnosed with mesothelioma in Australia each year. In 2021, 637 cases were diagnosed, and in 2022, there were over 900 cases.

More than 700 people die from mesothelioma each year in Australia. In 2020, there were 701 deaths, and in 2021, 708 deaths were recorded.

The 5-year relative survival rate for mesothelioma in Australia improved from 5.6% between 1989-1993 to 6.8% between 2014-2018. The 1-year relative survival rate has also increased over time.

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